Figure 1.

lncRNA FOXD2-AS1 was upregulated in cervical cancer

(A) m⁶A motifs were detected by m⁶A methylated RNA immunoprecipitation sequencing (MeRIP-seq). (B) The distribution situation of m⁶A modification included 3′ untranslated region (3′ UTR), CDS (coding sequence), 5′ UTR, and other regions. (C) Several candidate lncRNAs were detected using quantitative real-time RT-PCR and displayed using the heatmap. (D) FOXD2-AS1 expression was determined in cervical cancer cell lines (HT-3, C33A, CaSki, SiHa) and the normal cell line (HaCaT) using RT-PCR. (E) In cervical cancer tissue samples and normal tissue samples, RT-PCR detected the FOXD2-AS1 level. (F) Survival analysis using Kaplan-Meier test demonstrated the correlation within FOXD2-AS1 expression and survival of cervical cancer patients. All data were shown as mean ± SD. ∗∗p < 0.01.