Table 3.

Studies on Psycho-Social Processes Underlying Non-Adherence to Tamoxifen

Authors	Year	Type of Study	Patients (N)	Disease Stage	FUP Period	Nonadherence Measure	Nonadherence Rate	Psychological Processes Associated to Nonaadherence
Cahir et al.33	2015	Qualitative	31	I°-III°	3 Months	Interview	73%	Self-monitoring; Environmental stressors; Knowledge; Medication Beliefs; Time Perspective
Corter et al.71	2018	Survey	125	I°	3 Months	Pill count	36%	Health Beliefs
Cluze et al.39	2012	Prospective	218	Not available	10, 16, and 28 months	Two or more consecutive months without dispensed prescription of tamoxifen	42%	Fear of recurrence; Social Support; Patient-Doctor Communication; treatment options
Fink et al.38	2004	Cohort	516	I°-III°	3, 6, 15, and 27 months	Interview	21%	Medication Beliefs
Khan et al.40	2007	Cohort	881	I°-III°	4-yeras	Single item	21%%	involvement in decision-making
Liu et al.41	2013	Prospective	303	I°-III°	6, 18, and 36 months	Single item	36%	Patient-centered communication; Self-efficacy
Moon et al.36	2019	Longitudinal	345	I°-III°	3, 6 and 12 months	Medication Adherence Rating Scale	50%	Medication beliefs/Self-Confidence in ability to take tamoxifen
Moon et al.34	2017	Cross-sectional	777	I°-III°	1–2 years	Medication Adherence Report Scale	44%	Medication Beliefs
Pan et al.37	2018	Cohort	116	I°-III°	At 24 months	Single item	14.7%	Medication Beliefs/Optimism
Vaughn et al.35	2020	Prospective	89	Not available	Not available	Pill count	Not available	Delay discounting effect
Wassermann et al.29	2019	Cohort	384	I°-III°	At 30 months	Three-item	51%	Social-support/Confidence in Decision-Making
Wheeler et al.47	2019	Cohort	1280	I°-III°	2-years post-diagnosis-10 years post-diagnosis	Two-item	18.9%	Recurrence risk perception/
Yusufov et al.30	2021	Prospective	73	I°-II°	3–6 weeks	Two-item	77.9%	Anxiety/Depression/Somatosensory Amplification