Table 4.

Comparison of GABRG2 Rs211037 Genotype Distribution in Children with Epilepsy with or without VPA-Induced dADRs

Genetic Model	Genotype	Children with Epilepsy with dADRs(n=35)	Children with Epilepsy without dADRs (n=61)	P value	OR (95% CI)
Allele contrast	C vs T	36 (51.0%)/	43 (35.0%) /	0.028*	1.00
		34 (49.0%)	79 (65.0%)		1.95 (1.07–3.60)
Codominant	CC vs CT vs TT	10 (28.6%) /	6 (9.8%) /	0.054	1.00
		16 (45.7%) /	31 (50.8%) /		1.38 (0.52–3.65)
		9 (25.7%)	24 (39.3%)		4.44 (1.25–15.82)
Dominant	CT + CC vs.TT	26 (74.3%)/	37 (60.7%)/	0.17	1.00
		9 (25.7%)	24 (39.3%)		1.87 (0.75–4.68)
Recessive	CC vs CT+TT	10 (28.6%) /	6 (9.8%)/	0.037*	1.00
		25 (71.4%)	55 (90.1%)		3.67 (1.23–11.66)
Overdominant	CC + TT vs CT	19 (54.3%)/	30 (49.1%)/	0.63	1.00
		16 (45.7%)	31 (50.8%)		0.81 (0.35–1.87)
Log-additive	CC vs TT	10 (28.6%) /	6 (9.8%) /	0.027*	1.00
		9 (25.7%)	24 (39.3%)		4.44 (1.33–13.72)

Note: * P< 0.05.