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Schematics depicting plausible underlying mechanisms of how quercetin may abrogate SARS-CoV-2 infection and mitigate pathogenesis of COVID-19. SARS-CoV-2: severe acute respiratory syndrome coronavirus 2; ACE-2: angiotensin converting enzyme-2; 3CLpro: 3C-like proteases; NF-κB: nuclear factor kappa B; IL: interleukin; NLRP: nucleotide-binding oligomerization domain leucine rich repeat and pyrin domain-containing protein; NRF2: nuclear factor erythroid-derived 2-like 2.
