Skip to main content
. 2021 Aug 11;62:100105. doi: 10.1016/j.jlr.2021.100105

Fig. 7.

Fig. 7

Phenotype of the compound heterozygous LeprL536Hfs*6/db mouse. Comparison of LeprL536Hfs*6/db to LeprL536Hfs*6, wildtype (wt) and Leprdb/db mice with regard to (A) body weight gain between 4 and 10 weeks of age (n = 6–7, *sLeprL536Hfs*6/db vs. LeprL536Hfs*6 and Leprdb/db, †LeprL536Hfs*6/db vs. wt, two-way ANOVA). B: Relative organ weights (n = 3–7, two-way ANOVA). C: Whole body fat mass at 6 and 10 weeks of age measured by EchoMRI700™ (n = 6–7, two-way ANOVA). D: Body length (naso-anal-length) as well as tail length (n = 3–6, two-way ANOVA). E: body temperature (n = 5–6, unpaired t test), (F) fasting blood glucose (n = 5–6, unpaired t test), (G) HbA1c (n = 5–6, unpaired t test). Serum levels of (H): adiponectin (n = 4–5, unpaired t test), (I) leptin (n = 4–5, unpaired t test), (J) insulin (n = 5, unpaired t test) and (K) C-peptide (n = 4–5, unpaired t test) at 12 weeks of age. Data shown as mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001.