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Structural representation of different type-VI CRISPR-Cas13 orthologs with their approximated amino acid (aa) size of each Cas13 sub-type. Abbreviations: HEPN higher eukaryotes and prokaryotes nucleotide-binding domain, HTH helix-turn-helix domain, WYL WYL domain, TM transmembrane spanning the region. Within each CRISPR array, green diamonds symbolize the CRISPR repeats, while blue rectangles symbolize the spacer sequences
