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. 2021 Sep 6;8:706570. doi: 10.3389/fmolb.2021.706570

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Copyright © 2021 Jia, Liu, Lv, Qiao, Zhang, Niu, Shang, Liu, Dong and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Silencing LBX2-AS1 suppresses tumor growth of MM. (A) Representative images of nude mice treated with NCI-H929 cells that were transfected with shNC, shLBX2-AS1, empty vector and LBX2-AS1 overexpression. (B) Representative images of tumors from above nude mice after 5 weeks. (C) Detection of tumor weight after treatment for 5 weeks. (D) Detection of tumor volume in each week. (E, F) RT-qPCR examining the expression of LBX2-AS1 and LBX2 in tumor tissues from above nude mice after treatment for 5 weeks. ***p < 0.001; ****p < 0.0001.