FIGURE 2.

Summary of qualitative and quantitative echo assessments. Echo records were independently evaluated by qualified sonographers as described in section “Materials and Methods.” (A) Summary of qualitative echo findings. (B) Quantitation of RV and LV fractional shortening. Left panel, representative M-mode tracing, showing RV and LV chamber dimensions at systole (s) and diastole (d). Right panel, quantitation of RV fractional shortening. Each dot represents the average of fractional shortening values determined over 3–4 cardiac cycles in a single M-mode trace; multiple traces were obtained for each condition. (C) Quantitation of RV Fractional Area Change (FAC). FAC was determined from cinematic echo recordings over multiple cardiac cycles for each condition. (D) Quantitation of Eccentricity Index (EI). EI was determined from cinematic echo recordings over multiple cardiac cycles for each condition.