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. 2021 Sep 6;9:618492. doi: 10.3389/fcell.2021.618492

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Copyright © 2021 Lou, Zhou, Li, Lu, Bao, Yang, Liao, Chen, Fang, Yang, Lyu and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lipidomics analysis in the patient- and control-derived lymphocytes. (A) Relative palmitic acid content in the lymphocytes. (B) The quantification of membrane lipid components including phosphatidylglycerol (PG), phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylinositol (PI), and phosphatidylserine (PS). Relative amount of substance in (C) PG and (D) PC, analyzed based on fatty acid chain length. (E) The saturated fatty acids (SFAs), (F) monounsaturated fatty acids (MUFAs), and (G) polyunsaturated fatty acids (PUFAs) were analyzed in PG and PC, respectively. All data were from six independent replicates and analyzed by mean ± SEM. Independent t-test in panels (A–G). **p < 0.01, ***p < 0.001, ****p < 0.0001.