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. 2021 Sep 6;8:710567. doi: 10.3389/fcvm.2021.710567

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Copyright © 2021 Miao, Du, Chen, Shi and Qu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plot for the effect of microbiota-driven therapy on circulating TMAO level (subgroup analysis). The effect size of each trial or the overall was represented as black diamond and the weight of each trail in the overall study was represented as gray box around black diamond. The estimated 95% confidence interval of effect size was identified by extending lines. CI, confidence interval; RCT, randomized controlled trial; SMD, Standard Mean Difference.