FIG. 6.

Analyses with antisense ODNs. (A) Analysis of E2F4 and Sp1 proteins in extracts following ODN treatment of PC12 cells. PC12 cells were treated with NGF for 6 days in the presence or absence of ODNs. (B) Neurite outgrowth in PC12 cells following antisense-ODN treatment for 5 days. The percentage of total cells bearing neurites more than 2 cell body diameters in length were determined. Results are expressed relative to those for cells treated with NGF in the absence of ODNs and are the averages of five independent experiments. N, cells treated with NGF without ODN; C1, control unrelated ODN.