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8-MOP attenuated IL-1β-mediated cell apoptosis and proliferation inhibition. Rat chondrocytes were treated with IL-1β (20 ng/ml) and/or 8-MOP (20 and 40 µM) for 24 h. (A–C), MTT and FCM were applied to monitor cell proliferation and apoptosis, respectively. (D), Western blot was utilized to measure the expression of apoptotic related proteins, including Bax, Bcl2, and cleaved Caspase3. *p < 0.05, **p < 0.01, ***p < 0.001. (n = 3).
