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8-MOP weakened IL-1β-mediated inflammatory and oxidative stress responses. Rat chondrocytes were treated with IL-1β (20 ng/ml) and/or 8-MOP (20 and 40 µM) for 24 h. (A–F). The levels of inflammatory cytokines (IL-6, TNF-α, and IL-18) were detected by qRT-PCR and ELISA. (G–I): The oxidative stress factors (MDA, SOD, and GSH-PX) in chondrocytes were measured by the MDA, SOD, and GSH-PX detection kits. *p < 0.05, **p < 0.01, ***p < 0.001. (n = 3).
