TABLE 2.

Mechanism of action of antibacterial compounds of animal origin against Gram-negative strains.

Compound	Source	MIC value range	Action mechanism
Arenicin	Arenicola marina	1–2 µM	Membrane interaction - Outer-membrane lesions induced by current fluctuations in the lipid bilayer Andrä et al. (2008)
PGLa	Frog skin	≥64 μM	Putative mechanism -displacement of Mg2+ions from the lipopolysaccharide layer and PGLa insertion
Magainin	Xenopus laevis	75 mg L−1.	Permeabilization of bacterial membranes – efflux of intracellular K+ ions Matsuzaki et al. (1997)
Chitosan	Crustacean chitin	0.5–2.0 g/L	Peptidoglycan hydrolysis Goy et al. (2016)
Seroin	Bombyx mori	1–20 μg (depending on seroin type and exposure time)	Growth inhibition Singh et al. (2014)