Table 1.
Correlation Between p16 Expression and Clinic-Pathological Patient Data.
| Clinical data | N (%) | P16 expression | |
|---|---|---|---|
| Negative | Positive | ||
| Age (year) | |||
| ≤60 | 26 (35.1) | 20 | 6 |
| >60 | 48 (64.9) | 34 | 14 |
| P = 1.00 | |||
| Smoking habit | |||
| Smokers | 66 (89.1) | 50 | 16 |
| No-smokers | 8 (10.9) | 4 | 4 |
| P = .29 | |||
| Alcohol habit | |||
| Drinker | 58 (78.3) | 44 | 14 |
| No-drinker | 16 (21.7) | 10 | 6 |
| P = .64 | |||
| Primary site | |||
| Glottic | 26 (35.1) | 18 | 8 |
| Trans-supraglottic | 48 (64.9) | 36 | 12 |
| P = .71 | |||
| Histologic grade | |||
| G1 | 8 (10.9) | 8 | 0 |
| G2-G3 | 66 (89.1%) | 46 | 20 |
| P = .55a | |||
| T classification | |||
| T1-T2 | 34 (45.9) | 24 | 10 |
| T3-T4 | 40 (54.1%) | 30 | 510 |
| P = 1.00 | |||
| N clinical status | |||
| N0 | 26 (35.1) | 14 | 12 |
| N+ | 48 (68) | 30 | 8 |
| P = .02 | |||
| Treatment | |||
| Surgery alone | 36 | 22 | 14 |
| Surgery plus RT/CT | 38 | 34 | 6 |
| P = .14 | |||
aChi-squared test.