Figure 6. Neonatal morphine exposure does not impact adolescent behavior in the light-dark box test or elevated zero maze.

(A-B) In the light-dark box test female mice spent more time in the light compartment, had a lower latency to emerge, and made more transitions between the light and dark compartments compared to males. (C-D) In the elevated zero maze females spent more time in the open arm and had a lower latency to emerge compared to males. No effect of genotype or drug exposure was observed in the light dark box test or elevated zero maze. Data are expressed as mean ± SEM.