FIGURE 1.

Study design schematic illustrating observation windows for inclusion and exclusion criteria, covariate assessment, and outcome identification in relation to the index date (Day 0). ^ABaseline covariates include all conditions, medications, procedures, measurements (eg, laboratory testing), and medical devices used; as well as variables specific to rheumatoid arthritis severity. ^BEarliest of: outcome of interest, filling comparator study drug, disenrollment, end of the study period