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. 2021 Sep 14;16:6297–6311. doi: 10.2147/IJN.S323685

Figure 5.

Figure 5

Concentration-time curves of berberine hydrochloride (BBR) in the systemic circulation (A), portal vein (B), and livers (C) of mice receiving 200 mg/kg oral BBR, the complex of the natural nanoparticles (Nnps) and BBR (Nnps-BBR), and Coptidis Rhizoma extract, which all contained the corresponding dosage of BBR (Mean ± SD, n = 6).