TABLE 4.
Analysis of the discriminatory power of the binary typing method compared with other genotyping techniques, estimated on the basis of the typing results for epidemiologically unrelated MRSA strains from New York City and geographically diverse S. aureus strains from the United Statesa
| Strain | Binary code | Binary type | Result by indicated genotyping technique
|
|||
|---|---|---|---|---|---|---|
| PFGE | RAPD analyses | mecA-Tn554 probing | Methicillin resistanceb | |||
| K2-01 | 001110111110111 | 7671 | J | HMC | IV:M | R |
| K2-02 | 110001011100101 | 25317 | K | AAK | II:F | R |
| K2-06 | 001110111100111 | 7655 | L | NHB | III:NH | R |
| K2-07 | 000100100100111 | 2343 | M | CCC | II:NH | R |
| K2-12 | 001110100100111 | 7463 | J | HMC | IV:M | R |
| K2-13 | 101110111110101 | 24053 | M | NBB | II:NH | R |
| K2-19 | 001100100100101 | 6437 | J | MMC | IV:M | R |
| K2-20 | 011011111100001 | 14305 | N | NHB | II:NH | R |
| K2-21 | 111110011100001 | 31969 | O | NBB | II:NH | R |
| K2-22 | 000010111111111 | 1535 | P | BBB | I:unique | R |
| K2-24 | 001100000110111 | 6199 | Q | NNA | I:NH | R |
| K2-30 | 001110100110011 | 7475 | J | GOC | I:A | R |
| K2-31 | 011111110111101 | 16317 | R | NHB | II:NH | R |
| K2-32 | 001110100111111 | 7487 | J | HMC | IV:M | R |
| K2-34 | 011110111111101 | 15869 | S | NHB | II:NH | R |
| K2-38 | 011110111110101 | 15861 | T | BIB | I:A | R |
| K2-40 | 011110111110001 | 15857 | T | BBB | I:A | R |
| K2-44 | 001100101110011 | 6515 | U | MNA | I:E | R |
| K2-45 | 001110001100011 | 7267 | J | HMC | IV:M | R |
| K2-47 | 011110011100001 | 15585 | V | NHB | II:NH | R |
| K2-50 | 001111111101111 | 8175 | V | BBB | I:A | R |
| K2-51 | 101111111111101 | 24573 | V | BBB | I:A | R |
| K2-52 | 001111010110111 | 7863 | J | HMC | IV:M | R |
| K2-56 | 011110011110011 | 15603 | W | HMC | Unique:M | R |
| K2-57 | 000100110111101 | 2493 | X | JAE | I:D | R |
| K2-65 | 101110110100011 | 23971 | Y | PPH | Unique:E | R |
| SA-04 | 111010000000000 | 29696 | E | FSL | NH:X | S |
| SA-06 | 101110000100000 | 23584 | C | TTM | II:NH | I |
| SA-07 | 111110011100000 | 31968 | B | TTM | NH:NH | S |
| SA-08 | 111110011100001 | 31969 | G | VSL1 | I:NH | R |
| SA-11 | 100100001000000 | 18496 | F | VSL1 | II:NH | R |
| SA-12 | 111110001100000 | 31840 | A | TTM | I:A | R |
| SA-13 | 111110000110000 | 31792 | A | TTM | I:A | R |
| SA-14 | 100100000100000 | 18464 | H | TTM1 | NH:NH | S |
| SA-17 | 111110000010000 | 31760 | A | TTM | I:A | R |
| SB-02 | 000001101011111 | 863 | I | WUN | NH:NH | S |
| SB-09 | 111101110011111 | 31647 | I | WVN | NH:Z | S |
| SB-13 | 111101110011111 | 31647 | I | WVN | NH:NH | S |
| SC-06 | 101111110000111 | 24455 | Z | JXO | NH:NH | S |
| SC-08 | 100000000011000 | 16408 | Z | JXO | NH:NH | S |
| Total number of types | 38 | 25 | 19 | 11c | 3 | |
| D | 0.998 | 0.96 | 0.949 | 0.848 | ||
a
See Table 1 for more information on the origins of the strains used.
b
R, resistant; I, intermediately resistant; S, susceptible.
c
The mecA-Tn554 typing data for the MSSA strains (n = 8) were deleted.