Fig. 6.

High and low 5hmC clusters and their relation to survival and recurrence. Recursively partitioned mixture model (RPMM) of tumor samples of the top 10,000 most variable CpGs in tumor samples. In the heatmap, each column represents an individual sample and each row is a CpG. Two clusters emerged that correlated with average 5hmC and were so labeled high 5hmC (gray) and low 5hmC (black). Patient status as alive or dead is denoted under status and tracks with RPMM cluster as does tumor grade