. Author manuscript; available in PMC: 2022 Jan 3.

Published in final edited form as: AAPS PharmSciTech. 2021 Jan 3;22(1):18. doi: 10.1208/s12249-020-01892-w

Table IV.

Reporter Luciferase (Luc) DNA Loading Efficiency and Total Protein Content in Luc-EXOs and Luc-MVs derived from RAW 264.7 cells

Type of carrier	Amount of DNA transfected into cells (μg)^a	Amount of DNA in isolated EVs (ng)	DNA loading (%)^b	Total EV protein content (μg)^c
EXOs	0	516.3 ± 5.2	N/A	2361.2 ± 139.7
	12	586.8 ± 5.7	5.88 ± 0.48	2735.4 ± 71.3
	24	538.4 ± 4.1	1.85 ± 0.34	2090.7 ± 26.4
MVs	0	22.2 ± 0.2	N/A	441.6 ± 56.4
	12	29.6 ± 0.2	0.62 ± 0.01	460.0 ± 43.4
	24	28.3 ± 0.3	0.26 ± 0.01	375.2 ± 47.5