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. Author manuscript; available in PMC: 2021 Sep 20.
Published in final edited form as: Cell Rep. 2021 Apr 20;35(3):109012. doi: 10.1016/j.celrep.2021.109012

Figure 3. Cell type-specific role of caspase-11 in IL-18 and IL-1β activation during endotoxemia.

Figure 3.

(A–F) IL-18 and IL-1β amounts in the plasma of indicated mice 8 h post-LPS injection (20 mg/kg).

(G–J) IL-18 amounts in the spleen and liver of indicated mice 8 h post-LPS injection (20 mg/kg).

(K–P) IFN-β, TNF, and IL-6 amounts in the plasma of indicated mice 8 h post-LPS injection (20 mg/kg).

Combined data from two independent experiments are shown. Each circle represents a mouse, and the horizontal lines represent the mean. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; unpaired two-tailed t test (A, B, E–G, I, K, M, and O) and one-way ANOVA followed by Sidak’s post-test (C, D, H, J, L, N, and P). See also Figures S2 and S3.