Table 4.

Difference between gender (male and female), the two different age groups (<80 years and ≥80 years) and between patients with zero to seven drugs at the same time and patients using more than seven drugs (8–29) at the same time measured with FORTA, PRISCUS and EU(7)-PIM list (significant p values marked in bold)

		Patients (n)	PIM absolute
			(PIM (n)/drugs (n) (%))	Mean per patient	SD	Range	95% CI	P value
FORTA PIM	Male	1271	1126 (4.6)	0.89	1.00	0–5	0.83 to 0.94
	Female	1876	1726 (7.0)	0.92	1.05	0–7	0.87 to 0.97
								0.362
PRISCUS PIM	Male	1271	336 (1.4)	0.26	0.55	0–4	0.23 to 0.29
	Female	1876	627 (2.6)	0.33	0.60	0–4	0.31 to 0.36
								<0.001
EU (7)-PIM	Male	1271	1538 (6.3)	1.21	1.22	0–7	1.14 to 1.28
	Female	1876	2773 (11.3)	1.48	1.33	0–8	1.42 to 1.54
								<0.001
FORTA PIM	<80 years	2601	2293 (9.3)	0.88	1.02	0–7	0.84 to 0.92
	≥80 years	546	559 (2.3)	1.02	1.08	0–6	0.93 to 1.11
								0.005
PRISCUS PIM	<80 years	2601	744 (3.0)	0.29	0.57	0–4	0.27 to 0.31
	≥80 years	546	219 (0.9)	0.40	0.62	0–3	0.34 to 0.45
								<0.001
EU (7)-PIM	<80 years	2601	3519 (14.3)	1.35	1.29	0–8	1.30 to 1.40
	≥80 years	546	792 (3.2)	1.44	1.31	0–8	1.33 to 1.55
								0.145
FORTA PIM	0–7 drugs	1646	857 (3.5)	0.52	0.70	0–3	0.49 to 0.55
	8–29 drugs	1501	1995 (8.1)	1.32	1.16	0–7	1.27 to 1.39
								<0.001
PRISCUS PIM	0–7 drugs	1646	271 (1.1)	0.16	0.41	0–2	0.14 to 0.18
	8–29 drugs	1501	692 (2.8)	0.46	0.69	0–4	0.43 to 0.50
								<0.001
EU (7)-PIM	0–7 drugs	1646	1334 (5.4)	0.81	0.87	0–4	0.77 to 0.85
	8–29 drugs	1501	2977 (12.1)	1.98	1.39	0–8	1.91 to 2.05
								<0.001

FORTA, Fit fOR The Aged; PIM, potentially inappropriate medication.