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Serum levels of RORC inhibitor.
| Rat | Treatment | Concentration (nM) | |
|---|---|---|---|
| before | after | ||
| 1 | RORCi | 2491 | 2055 |
| 2 | RORCi | 1487 | 1576 |
| 3 | RORCi | 1425 | 1873 |
| 4 | Vehicle | 0 | 0 |
| 5 | Vehicle | 0 | 0 |
| 6 | Vehicle | 0 | 0 |
| 7 | RORCi | 3527 | 4691 |
| 8 | RORCi | 1187 | 4673 |
| 9 | RORCi | 1891 | 1762 |
| 10 | Vehicle | 0 | 0 |
| 11 | Vehicle | 0 | 0 |
| 12 | Vehicle | 0 | 0 |
RORCi serum exposure was measured in rats of both groups (RORCi vs vehicle) before the morning dose and 2-3 hours after the morning dose at 1 timepoint only: day 32/33 of treatment.
