TABLE 3.
Clinical performance of self-collected versus clinician collected vaginal/meatal swab samplesc
| Sample type | Total (N) | % Sensitivity (n/N) | 95% CI | % Specificity (n/N) | 95% CI |
|---|---|---|---|---|---|
| Female vaginal swab samplesa | |||||
| Clinician-collected | |||||
| Symptomatic Asymptomatic Overall |
335 207 542 |
100 (71/71) 96.4 (27/28) 99.0 (98/99) |
94.9–100 82.3–99.4 94.5–99.8 |
96.6 (255/264) 95.0 (170/179) 95.9 (425/443) |
93.6–98.2 90.7–97.3 93.7–97.4 |
| Self-collected | |||||
| Symptomatic Asymptomatic Overall |
288 247 535 |
100 (45/45) 100 (27/27) 100 (72/72) |
92.1–100 87.5–100 94.9–100 |
97.5 (237/243) 97.7 (215/220) 97.6 (452/463) |
94.7–98.9 94.8–99.0 95.8–98.7 |
| Male meatal swab samplesb | |||||
| Clinician-collected | |||||
| Symptomatic Asymptomatic Overall |
169 319 488 |
100 (7/7) 100 (7/7) 100 (14/14) |
64.6–100 64.6–100 78.5–100 |
91.4 (148/162) 93.3 (291/312) 92.6 (439/474) |
86.0–94.8 89.9–95.6 89.9–94.6 |
| Self-collected | |||||
| Symptomatic Asymptomatic Overall |
146 343 489 |
100 (6/6) 100 (4/4) 100 (10/10) |
61.0–100 51.0–100 72.2–100 |
90.7 (127/140) 93.2 (316/339) 92.5 (443/479) |
84.8–94.5 90.0–95.4 89.8–94.5 |
a
Overall difference in sensitivity (95% CI) and specificity (95% CI) for clinician-collected versus self-collected vaginal swabs was −1.0 (−3.0, 1.0), P = 1.00; and −1.7% (−4.0%, 0.6%), P = 0.21, respectively.
b
Overall difference in sensitivity (95% CI) and specificity (95% CI) for clinician-collected versus self-collected meatal swabs was 0% (−23.2%, 30.9%), P = 1.00; and 0.1% (−3.2%, 3.5%), P = 1.00, respectively.
c
CI, confidence interval; N, total number of samples; n, number of positive samples with accurate result (for sensitivity) or number of negative samples with accurate result (for specificity).