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UA reduces CCI4-induced liver fibrosis by inhibiting NOX4 and NLRP3 signaling. (a) IHC was used to examine the effect of UA on NOX4 (100×); (b) IHC was used to examine the effect of UA on NLRP3 (100×); (c) The relative mRNA expression of NOX4 and NLRP3 was measured by qRT-PCR. n = 6 per group. The data are presented as the means±SD in each group. *P < .050, **P < .010 and ***P < .001
