Figure 6.

Changes in gut microbial diversity in four groups of mice with CCI4 induced liver fibrosis. (a,b):α-diversity analysis (Chao1 index, Shannon index) in the four groups;(c-d): β-diversity analysis (PCoA, NMDS) in the four groups; (e): Diversity of gut bacteria at the genus level in the four groups. Abbreviation C: control group; M: WT+CCI4 group; P: NOX4^−/- +CCI4 group; X: NLRP3^−/- +CCI4 group. n = 4, 4, 4 of C, P, X group; n = 5 of M group. The data are presented as the means±SD in four groups. *P < .050, **P < .010 and ***P < .001