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. 2021 Sep 6;11:724435. doi: 10.3389/fonc.2021.724435

Figure 1.

Figure 1

The GNA15 gene was highly expressed in subjects with acute myeloid leukemia (AML). (A) In the ImmuCo database, the gene expression level of GNA15 was higher in leukemic stem cells (LSC, n=113) than in hematopoietic stem cells (HSC, n=263). (B) In the ONCOMINE database, GNA15 showed significantly higher expression in AML patients (n=542) than in normal peripheral blood mononuclear samples (PBMC, n=74). (C) The expression of GNA15 in various cancers and normal tissues was significantly different and GNA15 was overexpressed in AML in the GEPIA2 database. The height of the bar represents the median expression of GNA15 of a certain tumor or normal tissue. (D) GNA15 transcript levels in normal volunteers, acute lymphoblastic leukemia (ALL) and AML. (E) GNA15 transcript levels in AML with or without FLT3-ITD mutation. (F) GNA15 transcript levels in AML with or without AML1-ETO fusion gene. Error bars indicate median with interquartile range (D–F).