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. 2021 Sep 6;11:724435. doi: 10.3389/fonc.2021.724435

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Copyright © 2021 Li, Liu, Liu, Yang, Xu, Wang, Jiang, Liu, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GNA15 knockdown reduces the proliferation ability of AML cells in nude mice by inhibiting the P38 MAPK signaling pathway. (A–D) GNA15-KD inhibits tumor growth in Kasumi-1 and SKNO-1 cells. (E) The expression of P38 MAPK signaling pathway proteins in tumor tissues by Western blot. CTRL, control; KD, knockdown; ***P < 0.001 compared with CTRL cells. Error bars indicate the standard deviation.