Table 1.
Sociodemographic characteristics and descriptive statistics of the whole cohort according to the primary motivation for office evaluation (n=7447)
| Parameters | LUTS | ED | Infertility | P |
|---|---|---|---|---|
| Patients, n (%) | 1912 (25.7) | 2944 (39.5) | 2591 (34.8) | |
| Age (year) | <0.001 | |||
| Median (IQR) | 57 (45–66)* | 46 (33–58)* | 36 (33–40) | |
| Range | 18–85 | 18–70 | 18–60 | |
| BMI (kg m−2) | <0.001 | |||
| Median (IQR) | 25 (23–27) | 25 (23–27)* | 25 (23–27) | |
| Range | 15–43 | 15.6–51 | 18–55 | |
| CCI score | <0.001 | |||
| Median (IQR) | 0 (0–1)* | 0 (0–1)* | 0 (0–2) | |
| Mean (s.d.) | 0.3 (0.3) | 0.3 (0.2) | 0.1 (0.2) | |
| Range | 0–8 | 0–9 | 0–8 | |
| CCI ≥1, n (%) | 364 (19.0) | 542 (18.4) | 193 (7.5) | <0.001 |
| IPSS score | <0.001 | |||
| Median (IQR) | 18 (7–20) | 8 (3–11) | ||
| Range | 0–35 | 0–32 | ||
| IIEF-EF score | <0.01 | |||
| Median (IQR) | 19 (8–28) | 15 (8–22) | ||
| Range | 0–30 | 0–30 | ||
| Smoking status, n (%) | <0.001 | |||
| Nonsmokers/former smokers | 1542 (80.7)* | 2172 (73.8) | 1780 (68.7) | |
| Active smokers | 370 (19.3) | 772 (26.2) | 811 (31.3) | |
| Smoking quantity, n (%) | 0.87 | |||
| Moderate smokers | 236 (12.4) | 494 (16.7) | 511 (19.7) | |
| Heavy smokers | 134 (7.0) | 278 (9.4) | 300 (11.6) | |
| Alcohol consumption, n (%) | <0.001 | |||
| Never | 378 (19.8)* | 491 (16.7) | 391 (15.1) | |
| Active consumption | 1534 (80.2) | 2453 (83.3) | 2200 (84.9) | |
| Alcohol quantity, n (%) | <0.001 | |||
| Moderate drinkers | 1021 (53.4) | 1720 (58.4) | 1683 (64.9) | |
| Heavy drinkers | 513 (26.8) | 733 (24.8) | 517 (19.9) | |
| SoA, n (%) | <0.001 | |||
| Never | 1821 (95.2)* | 2744 (93.2) | 2314 (89.3) | |
| Former users | 74 (3.9) | 134 (4.6) | 170 (6.6) | |
| Active users | 17 (0.9) | 66 (2.2) | 107 (4.1) | |
| Type of current SoA use, n (%) | ||||
| Cannabis/marijuana/hashish | 12 (0.6) | 53 (1.8) | 82 (3.2) | 0.66 |
| Cocaine | 5 (0.3) | 23 (0.8) | 25 (0.9) | 0.26 |
| Heroin (different forms) | 1 (0.05) | 4 (0.1) | 5 (0.2) | 0.38 |
| Other illicit drugs | 2 (0.1) | 5 (0.2) | 16 (0.6) | 0.35 |
| Multiple SoA use, n (%) | 3 (0.2) | 18 (0.6) | 20 (0.7) | 0.37 |
P value according to the Kruskal–Wallis test and the Fisher’s exact test, as indicated. *P<0.01 for selected group versus infertility group. BMI: body mass index; CCI: Charlson Comorbidity Index; SoA: substances of abuse; IPSS: International Prostate Symptom Score; IIEF-EF: International Index of Erectile Function-Erectile Function domain; LUTS: lower urinary tract symptom; ED: erectile dysfunction; s.d.: standard deviation; IQR: interquartile range