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. 2007 Jul 18;2007(3):CD002739. doi: 10.1002/14651858.CD002739.pub3

Yazigi 1978.

Methods RCT, double‐blind, crossover 
 2 dropouts due to negative result on exercise testing with placebo. 
 Concomitant treatment: triamcinolone acetonide which was withheld for 12 hours before the exercise test. 
 Exercise test: treadmill ( 6 minutes, 3 mph, 15% grade)
Participants N=11. 6 m, 5 f. Age: 8‐15 years. All had EIB as defined by fall in FEV1 of at least 15% after exercise in the last one week. All participants were already receiving triamcinolone acetonide aerosol ( 100mcg od ‐ 300 mcg qid) for control of severe asthma.
Interventions In random order: A single dose of triamcinolone acetonide inhaler 300 mcg or placebo inhaler 15 minutes before exercise test. 24 hour washout period in‐between.
Outcomes PEF, FEV1, FEF25‐75% vital capacity were measures immediately before exercise, and at 5 min interval for 15 min.
Notes Jadad score =3
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk Information not available