Methods |
RCT, double‐blind, crossover
2 dropouts due to negative result on exercise testing with placebo.
Concomitant treatment: triamcinolone acetonide which was withheld for 12 hours before the exercise test.
Exercise test: treadmill ( 6 minutes, 3 mph, 15% grade) |
Participants |
N=11. 6 m, 5 f. Age: 8‐15 years. All had EIB as defined by fall in FEV1 of at least 15% after exercise in the last one week. All participants were already receiving triamcinolone acetonide aerosol ( 100mcg od ‐ 300 mcg qid) for control of severe asthma. |
Interventions |
In random order: A single dose of triamcinolone acetonide inhaler 300 mcg or placebo inhaler 15 minutes before exercise test. 24 hour washout period in‐between. |
Outcomes |
PEF, FEV1, FEF25‐75% vital capacity were measures immediately before exercise, and at 5 min interval for 15 min. |
Notes |
Jadad score =3 |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Allocation concealment? |
Unclear risk |
Information not available |