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. 2021 May 18;19(3):227–237. doi: 10.1080/2090598X.2021.1926752

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Comparative FFOCT and H&E-stained histology. (a) Testis of a normal rat shows seminiferous tubules with relatively uniform size and shape, (b) H&E histology stain of the same specimen. Arrows point to the sperm within the tubule lumen. (c) Seminiferous tubules in the testis of a rat treated with busulfan, showing thinner tubules and a greater degree of heterogeneity in size and shape with ~10% normal spermatogenesis. (d) H&E staining of the same specimen. Field of view in each panel: 1 mm² Permission granted under the creative commons attribution license, Ramasamy et al. [19]