Supplemental Table.
Results of the 2-way ANOVA for repeated measures for cardiovascular and hematologic variables measured over time. P-values for the main effects of treatment and time and treatment by time interaction were included in the analysis.
| P-value | P-value | P-value | |
|---|---|---|---|
| Variable | Time | Treatment | Treatment by time |
| HR (beats/min) | 0.4371 | 0.1804 | 0.0001 |
| CI (mL/kg/min) | 0.0877 | 0.0018 | 0.0011 |
| MAP (mmHg) | 0.0003 | 0.0152 | < 0.0001 |
| DO2(mL/min/kg) | 0.0385 | 0.2814 | < 0.0001 |
| SAP (mmHg) | 0.0002 | 0.0859 | 0.2188 |
| DAP (mmHg) | < 0.0001 | < 0.0122 | < 0.0001 |
| CVP (mmHg) | < 0.0001 | 0.8037 | < 0.0001 |
| MPAP (mmHg) | 0.0526 | 0.1048 | 0.6612 |
| PAOP (mmHg) | 0.0005 | 0.7320 | 0.6047 |
| SI (mL/beat/kg) | < 0.0001 | 0.1664 | 0.0960 |
| SVRI (dynes.s/cm5/kg) | 0.0011 | 0.7916 | 0.2534 |
| PVRI (dynes.s/cm5/kg) | 0.1131 | 0.4441 | 0.9927 |
| VO2 (mL/min/kg) | 0.8854 | 0.5871 | 0.3281 |
| HCT (%) | 0.6460 | 0.05575 | 0.1409 |
| TS (g/dL) | 0.0865 | 0.2618 | 0.3130 |
| Lactate (mmoL/L) | 0.0586 | 0.0754 | 0.2497 |
| Temperature (°C) | < 0.0047 | < 0.0001 | < 0.0001 |
HR — heart rate; CI — cardiac index; MAP — mean arterial pressure; DO2 — oxygen delivery; SAP — systolic arterial pressure; DAP — diastolic arterial pressure; CVP — central venous pressure; MPAP — mean pulmonary arterial pressure; PAOP — pulmonary artery occlusion pressure; SI — stroke index; SVRI — systemic vascular resistance index; PVRI — pulmonary vascular resistance index; VO2 — oxygen consumption; HCT — hematocrit; TS — transferrin saturation.