TABLE 6.
In‐hospital outcomes stratified by timing of insertion of Impella 2.5 and CP in relation to the interventional procedure in patients with high‐risk PCI
| Combined (N = 174) | Before (N = 117) | During/after (N = 57) | p‐value | |
|---|---|---|---|---|
| In‐hospital outcomes | ||||
| Death | 6%10 | 3%3 | 12%7 | .02 |
| Life‐threatening or severe bleeding | 3%6 | 1%1 | 9%5 | .02 |
| Number of red blood cell transfusions | 2 [1;3] | 2 [2;3] | 1 [1;2] | .20 |
| Device‐related complications | 10%17 | 7%8 | 16%9 | .11 |
| Access‐site bleeding | 7%12 | 4%5 | 12%7 | .06 |
| Limb ischemia | 2%4 | 3%3 | 2%1 | 1 |
| Need for endovascular intervention | 2%4 | 3%3 | 2%1 | 1 |
| Aortic injury | 0% (0) | 0% (0) | 0% (0) | NA |
| Left ventricular perforation | 0% (0) | 0% (0) | 0% (0) | NA |
| Sepsis | 4%7 | 6%7 | 0% (0) | .10 |
| Acute kidney injurya | 13%19 | 16%14 | 9%5 | .31 |
| Need for renal replacement therapy | 4%6 | 3%3 | 5%3 | .39 |
| Escalation therapyb | 0% (0) | 0% (0) | 0% (0) | NA |
| LVEF at discharge, % | 32 [26;40] | 33 [26;40] | 30 [25;36] | .23 |
Note: In‐hospital outcomes are reported as n (%) or median (interquartile range) as appropriate. One‐year outcomes are reported as number of events (Kaplan–Meier failure estimate [95% confidence interval]).
Abbreviation: LVEF, left‐ventricular ejection fraction.
a
Defined as a serum creatinine increase ≥0.3 mg/dl from baseline.
b
Defined as the need for extracorporeal membrane oxygenation, other left ventricular assist device implantation or heart transplant.