Figure 4.

Oligodendrocyte population is not altered in MAPT^P301S mice at P120 and P180. (a‐l) Representative confocal images of ASPA (red) and Hoechst 33342 (blue) in the hippocampus (a‐d), entorhinal cortex (EC; e‐h) and fimbria (i‐l) of wild‐type (WT) and MAPT^P301S mice at P120 and P180. (m‐o) Quantification of total oligodendrocyte density (ASPA⁺/mm²) in the hippocampus [(m): two‐way ANOVA, genotype: F (1, 17) = 0.417, p = .526; age: F (1, 17) = 0.849, p = .369; interaction: (1, 17) = 1.100, p = .308], the entorhinal cortex [(n): two‐way ANOVA, genotype: F (1, 18) = 0.004, p = .948; age: F (1, 18) = 0.0254, p = .875; interaction: F (1, 18) = 0.397, p = .536] and the fimbria [(o): two‐way ANOVA, genotype: F (1, 14) = 0.594, p = .453; age: F (1, 14) = 1.145, p = .302; interaction: F (1, 14) = 0.080, p = .781] of WT (open circles, black bars) and MAPT^P301S (black squares, open bars) mice at P120 and P180. Data are presented as mean ± SD, n = 3–5 mice per group. Scale bars represent 40 µm