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. 2021 Sep 6;9:689962. doi: 10.3389/fcell.2021.689962

TABLE 5.

The most important epigenetic compounds that can affect angiogenesis.

Compounds Function References
Trichostatin A Inhibits histone deacetylases Deroanne et al., 2002
Suberoylanilide hydroxamic acid Inhibits histone deacetylases Marks, 2007
Valproic acid HDAC inhibitor Michaelis et al., 2004
Sodium butyrate HDAC inhibitor Pellizzaro et al., 2002
5-azacytidine and 5-aza-2′deoxycytidine DNMT inhibitors Hellebrekers et al., 2006
Zebularine DNA methylation inhibitor Patnaik and Anupriya, 2019
GSK343 Inhibits histone H3K27 methylation Yu et al., 2017
Panobinostat Induces acetylation of histone H3 Zhi-Gang et al., 2017
Curcumin Inhibitor of DNMTs Hassan et al., 2019
Sulforaphane Suppress HDACs Shankar et al., 2008