Table 3.

Multivariable Cox regression analysis showing hazard ratio of a positive SARS-CoV-2 result during follow-up with vaccination in all patients and across different age, ethnic, gender, and IMD decile groups up to day 60 post vaccination.^a

Variables		Hazard ratio (95% CI)		P value
Vaccination
	No vaccination (reference)	1	N/Ab
	Vaccination	0.64 (0.43-0.95)	.03
Age (years)
	16-49 (reference)	1	N/A
	50-54	0.75 (0.58-0.98)	.03
	55-59	0.82 (0.64-1.06)	.13
	60-64	0.79 (0.61-1.02)	.07
	65-69	0.41 (0.32-0.54)	<.001
	70-74	0.26 (0.20-0.33)	<.001
	75-79	0.29 (0.23-0.38)	<.001
	≥80	0.29 (0.24-0.36)	<.001
Care home resident		0.76 (0.56-1.05)		.13
Clinically extremely vulnerable		0.30 (0.24-0.38)		<.001
Ethnicity
	White (reference)	1	N/A
	Asian or British Asian	0.91 (0.80-1.02)	.11
	Black or Black British	0.98 (0.77-1.25)	.89
	Mixed	1.29 (0.91-1.82)	.15
	Other ethnic groups	1.06 (0.83-1.35)	.65
Gender
	Female (reference)	1	N/A
	Male	1.02 (0.91-1.15)	.69
IMDc decile
	1 (reference)	1	N/A
	2	1.03 (0.74-1.43)	.87
	3	1.11 (0.82-1.51)	.49
	4	0.97 (0.71-1.32)	.83
	5	1.08 (0.79-1.48)	.62
	6	1.04 (0.76-1.42)	.79
	7	0.80 (0.58-1.12)	.24
	8	0.84 (0.59-1.20)	.33
	9	0.93 (0.65-1.34)	.72
	10	0.83 (0.56-1.21)	.33

^aCox regression model included an interaction term between having the vaccination and individual patient groups (age, ethnicity, gender, IMD decile).

^bN/A: not applicable.

^cIMD: index of multiple deprivation.