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. Author manuscript; available in PMC: 2022 Jan 19.
Published in final edited form as: Circ Heart Fail. 2021 Jan 19;14(1):e007300. doi: 10.1161/CIRCHEARTFAILURE.120.007300

Figure 2. CRD-733 reverses TAC-induced left ventricular (LV) hypertrophy.

Figure 2.

Figure 2.

Figure 2.

Figure 2.

Figure 2.

Figure 2.

Figure 2.

A, Left ventricular wet weight normalized to tibia length after 21 days. B, Change in echo-derived LV mass from start of treatment (day 7) to end of study (day 21), C, septal wall thickness and D, LV posterior wall thickness after 14 days of drug treatment. Apical LV tissue gene expression for E, Nppa, F, Nppb and G, Myh7. Results are expressed as mean ± SEM. Comparisons were performed using 1-way ANOVA with Tukey’s post-test; n=10-17 (A-D) or n=7-8 (E-G).