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. 2021 Sep 8;17(9):e1009783. doi: 10.1371/journal.pgen.1009783

Table 5. Hazard difference estimates (LoF carriers versus non-carriers) on percentage scale for all single and combined estimates.

Estimator Estimate (% scale) S.E p-value Combined Estimates
Q statistic Q p-value Combine?
CAT 2.2 0.210 0.0e+00
GMTE(0) -3.9 × 10−3 7.5 × 10−3 6.1e-01
GMTE(1) 0.28 0.140 4.8e-02
MR 0.29 0.110 7.9e-03
RGMTE 0.33 0.160 3.7e-02
RGMTE/MR 0.3 0.089 7.5e-04 0.05 8.3e-01 Yes
RGMTE/CAT 1.0 0.130 2.0e-15 49 2.4e-12 No
MR/CAT 0.68 0.096 9.1e-13 64 1.3e-15 No
GMTE(1)/CAT 0.86 0.120 1.0e-13 56 5.9e-14 No
RGMTE/MR/CAT 0.59 0.082 6.6e-13 68 2.1e-15 No