Table 1.
HTL epitopes selected for vaccine construct against Klebsiella oxytoca
| Protein ID | Alleles | Start | End | Method | Peptide sequence | Percentile rank | Adjusted rank | Allergenicity score | Antigenicity | IFN epitope score |
|---|---|---|---|---|---|---|---|---|---|---|
| A0A0H3HBY6 | HLA-DRB5*01:01 | 3 | 17 | Consensus (smm/nn/sturniolo) | EKKVVMRIRALHKRF | 0.21 | 0.21 | − 0.4281 | 0.57 | 0.030451 |
| HLA-DRB5*01:01 | 6 | 20 | Consensus (smm/nn/sturniolo) | VVMRIRALHKRFGAQ | 0.58 | 0.58 | − 0.598 | 1.24 | 0.013655 | |
| HLA-DRB5*01:01 | 2 | 16 | Consensus (smm/nn/sturniolo) | SEKKVVMRIRALHKR | 0.21 | 0.21 | − 0.5404 | 0.46 | 0.188259 | |
| A0A0H3HCH0 | HLA-DRB3*02:02 | 142 | 156 | NetMHCIIpan | QQRVAIARALAMKPS | 3.6 | 3.6 | − 4.5988 | 0.73 | 0.336966 |
| A0A0H3HAB9 | HLA-DRB3*01:01 | 117 | 131 | Consensus (comb.lib./smm/nn) | HVKGMKRDEAKAIAM | 0.71 | 0.71 | − 0.5438 | 2.1 | 0.206067 |
| HLA-DRB3*01:01 | 115 | 129 | Consensus (comb.lib./smm/nn) | LLHVKGMKRDEAKAI | 0.72 | 0.72 | − 0.4656 | 0.75 | 0.055908 | |
| HLA-DRB3*01:01 | 118 | 132 | Consensus (comb.lib./smm/nn) | VKGMKRDEAKAIAMQ | 0.72 | 0.72 | − 0.5340 | 0.49 | 0.170946 | |
| HLA-DRB3*01:01 | 116 | 130 | Consensus (comb.lib./smm/nn) | LHVKGMKRDEAKAIA | 0.74 | 0.74 | − 0.5529 | 0.63 | 0.105924 | |
| A0A0H3HGA0 | HLA-DRB5*01:01 | 85 | 99 | Consensus (smm/nn/sturniolo) | TVSRFMLLRPGTHKR | 0.88 | 0.88 | − 0.7711 | 0.42 | 0.602909 |
| HLA-DRB1*03:01 | 15 | 29 | Consensus (smm/nn/sturniolo) | GQRRVLSDISLTLKP | 1.1 | 1.1 | − 9.901 | 0.53 | 0.3684091 | |
| A0A0H3HDE1 | HLA-DRB1*03:01 | 151 | 165 | Consensus (smm/nn/sturniolo) | HGWSAVNVDDRWLFR | 0.24 | 0.24 | − 0.5072 | 0.58 | 0.937815 |
| A0A0H3H729 | HLA-DRB5*01:01 | 214 | 228 | Consensus (smm/nn/sturniolo) | RSVTRAFNHMAAGVK | 0.16 | 0.16 | − 0.697 | 1.43 | 0.509832 |