Table 2. Summary of studies selected for the variable left ventricular developed pressure (LVDP), mm Hg.

Author (year)	Type of exercise	Intervention protocol	DOX injection	Left ventricular developed pressure (LVDP), mm Hg
				Control + DOX		Aerobic exercise + DOX
				n	${\overline{\text{X}}}_{\text{SD}}$	n	${\overline{\text{X}}}_{\text{SD}}$
Chicco et al. (2005)25	Aerobic Running wheel	Free access 24 h/day Total: 8 weeks	10 μM single dose post exercise	7	30.5 ± 1.4	7	50.1 ± 7.7
Chicco et al. (2006)26	Aerobic Treadmill	15-27 m/min 0°-5° 20-60 min/day 5 days/week Total: 12 weeks	15 mg/kg single dose post exercise	15	46 ± 9	15	84 ± 7
Hayward et al. (2012)18	Aerobic Running wheel	Free access 24 h/day Total: 10 weeks	2 mg/kg for 7 days Total = 14 mg/kg during exercise	22	91 ± 15†	22	121 ± 12†
Jensen et al. (2013)(a)22	Aerobic Treadmill	13-30 min/m 5º-18 m 20-60 min/day 5 days/week Total: 10 weeks	10 mg/kg single dose post exercise	14	70 ± 3††	10	93 ± 3††
Jensen et al. (2013)(b)22	Aerobic Running wheel	Free access 24 h/day Total: 10 weeks	10 mg/kg single dose post exercise	14	70 ± 3††	10	89 ± 2††

DOX: doxorubicin; x: mean; SD: standard deviation; (a) and (b) are subdivisions of the study conducted by Jensen et al. (2013);

^†measurement done with 300 beats per minute;

^††measurement done on the 9th day after DOX injection.