Table 3. Cochrane collaboration tool for evaluation of the risk of bias.
| Author (year) | Randomization | Concealment of randomization | Blinding of participants* | Blinding of evaluators* | Incomplete outcomes | Selective outcome reporting | Other sources of bias | Risk of bias |
|---|---|---|---|---|---|---|---|---|
| Chicco et al. (2005) | Low | Low | Low | Low | Low | Low | Low | Low |
| Chicco et al. (2006) | Low | Low | Low | Low | Low | Low | Low | Low |
| Hayward et al. (2012) | Low | Low | Low | Low | Low | Low | Low | Low |
| Hydock et al. (2012) | Low | Low | Low | Low | Low | Low | Low | Low |
| Calvé et al. (2012) | Low | Low | Low | Low | Low | Low | Low | Low |
| Jensen et al. (2013) | Low | Low | Low | Low | Low | Low | Low | Low |
| Dolionsky et al. (2013)21 | Low | Low | Low | Low | Low | Low | Low | Low |
| Parry et al. (2015)23 | Low | Low | Low | Low | Low | Low | Low | Low |
| Lien et al. (2015)24 | Low | Low | Low | Low | Low | Low | Low | Low |
*
The items referring to randomization and blinding of the sample were considered as low risk of bias even when not stated in the randomized controlled trial, given that studies of murine models neutralize these biases.