Table 4. The COVID-19/heart disease/pregnancy triad: features and differential diagnosis.

	COVID-19	Cardiopathy	Normal pregnancy
Symptoms	Fever (> 37.8 °C), myalgia, fatigue, anorexia, sore throat, nasal and conjunctival congestions, cough, dyspnea, anosmia, , odynophagia, nausea, vomiting, diarrhea, abdominal pain	Dyspnea/palpitations, chest pain, syncope, hemoptysis, fatigue, lower limb edema, orthopnea, dry cough	Nausea, vomiting, edema/dyspnea/fatigue, palpitations, dizziness, epistaxis, gestational rhinitis, headache, abdominal pain
Occurrence of symptoms according to gestational age	Any gestational age or puerperium	Usually during second and third trimesters of pregnancy or in the puerperium	Any gestational age
History	No previous heart disease	Previous heart disease	No previous heart disease
Laboratory aspects	Positive nasopharyngeal COVID-19 RT-PCR swab test lymphocytopenia Increased ALT/AST Increased urea/creatinine Increased D-dimer	High levels of BNP	Normal or slightly increased D-dimer
Imaging exams	Normal echocardiogram Chest X-ray with or without alterations Chest computed tomography imaging - ground-glass opacity	Echocardiogram - structural cardiac lesion Chest X-ray/computed tomography imaging alterations: cardiomegaly and/or pulmonary congestion	Normal echocardiogram Normal chest-X-ray

ALT: alanine aminotransferase; AST: aspartate aminotransferase; BNP: B-type natriuretic peptide; RT-PCR: reverse transcriptase-polymerase chain reaction.