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. 2021 Apr 5;5(5):683–691. doi: 10.1002/ags3.12460

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© 2021 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterological Surgery

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Immune cell populations in the Peyer's patch. (A) The CD4⁺ cell population was increased in the bacterial translocation (BT) group (P < .05) compared to the control group but decreased in the TU‐100 group (P < .05). (B) The Foxp3⁺ cell population was increased in the BT group compared to the control group (P < .05) and further increased in the TU‐100 group compared to the BT group. (C) The CD8⁺ cell population was increased in the BT group (P < .05) compared to the control group but significantly decreased in the TU‐100 group. Only administration of TU‐100 also induced the increase of CD8⁺ cell population (P < .05). *P < .05, **P < .01, ***P < .001