Table 1.
Baseline demographic and clinical features in the matched population.
| Variable | Lipiodol-TACE, n = 101 | DEB-TACE, n = 101 | p | SMD | |
|---|---|---|---|---|---|
| Age (years) | Mean ± sd | 63.4 ± 10.2 | 62.6 ± 10.7 | 0.60 | 0.077 |
| Range | 34-85 | 44-85 | |||
| Gender (male) | Male/female | 80/21 | 83/18 | 0.59 | − 0.075 |
| Cause of cirrhosis | No | 1 (1.0) | 4 (4.0) | 0.46 | − 0.192 |
| HCV | 52 (51.5) | 59 (58.4) | − 0.140 | ||
| HBV | 19 (18.8) | 19 (18.8) | 0 | ||
| HCV and HBV | 2 (2.0) | 2 (2.0) | 0 | ||
| Alcohol | 20 (19.8) | 10 (9.9) | 0.281 | ||
| Dysmetabolic | 5 (4.9) | 4 (4.0) | 0.048 | ||
| Other* | 2 (2.0) | 3 (2.9) | − 0.064 | ||
| Child-Pugh | A | 91 (90.1) | 80 (79.2) | 0.09 | 0.306 |
| B | 9 (8.9) | 17 (16.8) | − 0.238 | ||
| C | 0 | 0 | 0 | ||
| Alpha-fetoprotein (μg/L) | Mean ± sd | 1770 ± 9930 | 1067 ± 4686 | 0.68 | 0.091 |
| Median [25th-75th percentile] | 24.9 [8.5-174.5] | 11.2 [5.5-37] | |||
| Albumin (g/dL) | Mean ± sd | 3.68 ± 0.43 | 3.65 ± 0.47 | 0.61 | 0.075 |
| Total bilirubin (mg/dL) | Mean ± sd | 1.13 ± 0.64 | 1.22 ± 0.76 | 0.38 | − 0.127 |
| Creatinine (mg/dL) | Mean ± sd | 0.86 ± 021 | 0.86 ± 020 | 0.99 | − 0.01 |
| BCLC stage | 0 | 8 (7.9) | 8 (7.9) | 1.0 | 0 |
| A | 57 (56.4) | 57 (56.4) | 0 | ||
| B | 35 (34.7) | 35 (34.7) | 0 | ||
| C | 1 (1.0) | 1 (1.0) | 0 | ||
| Tumor extension | Unifocal | 53 (52.5) | 53 (52.5) | 1.0 | 0 |
| Unilobar | 77 (76.2) | 77 (76.2) | 1.0 | 0 | |
| Diameter of largest lesion (mm) | Mean ± sd | 34.8 ± 17.8 | 37.9 ± 21.2 | 0.26 | − 0.158 |
| Range | 12 - 110 | 10 - 140 | |||
| < 30 | 43 (42.6) | 36 (35.6) | 0.142 | ||
| 30-50 | 40 (39.6) | 40 (39.6) | 0 | ||
| 50-70 | 13 (12.9) | 19 (18.8) | − 0.163 | ||
| > 70 | 5 (4.9) | 6 (5.9) | − 0.044 |
*Other: autoimmune (n=1) and cryptogenetic (n=4)
When not otherwise specified, data are given as numbers (and percentages)
SMD, standard mean difference; NA, not applicable