Table 1.
Patient population clinical and demographic characteristics. Continuous data are presented as a median and interquartile range, ordinal data as value counts, and categorical data as proportions
| Site 1 | Site 2 | Site 3 | ||
|---|---|---|---|---|
| Age (years) | 66 (60–72) | 67 (60–69) | 67 (63–71) | p = 0.32 |
| PSA (ng/ml) | 7.1 (5.12–10.00) | 6.93 (5.51–9.78) | 8.00 (5.35-9.76) | p = 0.89 |
| ISUP grade§ | 1 = 1 | 1 = 1 | 1 = 5 | p = 0.21 |
| 2 = 40 | 2 = 21 | 2 = 15 | ||
| 3 = 43 | 3 = 16 | 3 = 8 | ||
| 4 = 17 | 4 = 4 | 4 = 14 | ||
| 5 = 3 | 5 = 1 | 5 = 5 | ||
| PI-RADS score# | 3 = 3 | 3 = 7 | 3 = 3 | p = 0.02* |
| 4 = 68 | 4 = 24 | 4 = 19 | ||
| 5 = 33 | 5 = 12 | 5 = 25 | ||
| EPE (pathologically proven) | 37/104 | 19/43 | 20/47 | p = 0.55 |
PSA, prostate-specific antigen; ISUP, International Society of Urological Pathology; PI-RADS, Prostate Imaging and Reporting Data System; EPE, extraprostatic extension of disease
*Post hoc analysis showed a significant difference exclusively between sites 2 and 3 (p = 0.008)
§As originally assigned by the pathologist on the radical prostatectomy specimen
#Obtained from the original radiology report