Figure 7.

HDAC6 inhibition improves ALS-dependent impairments in NMJ morphology

(A) Confocal micrographs of NMJs with TubA treatment. Scale bar, 10 μm.

(B) Quantification of NMJs as Btx-SYP/NEFH co-localization per myotube with and without TubA treatment. Control data without TubA treatment are identical to Figure 5B.

(C) Morphological analysis of NMJs without (C) and with TubA treatment. Control data (C) are identical to Figure 5C. Mean ± SEM from three to four biological replicates. One-way ANOVA with Tukey's multiple comparisons test or Kruskal-Wallis test with Dunn's multiple comparisons test. ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001.

See also Figures S4 and S7.