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. 2021 Sep 20;11:18641. doi: 10.1038/s41598-021-97535-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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CTA1-DD-RBF reduced hRSV replication and induced neutralizing antibodies in mice. (A) The lung viral load was measured on day 4 after hRSV A Long challenge. Each data point indicates a mouse. (B) IgA in the bronchoalveolar lavage fluid was detected using ELISA with RBF (100 ng/well) as the coating antigen. Statistically significant differences were measured by one-way ANOVA with the Newman-Keuls posttest, ***p < 0.001. The bars represent the mean values with standard deviations.