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. 2021 Sep 20;12:5530. doi: 10.1038/s41467-021-25708-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Tumor location for 23 MB-RIG and 9 ALL-RIG illustrated with circled numbers indicating the number of patients with RIG occurrence in the respective brain region (a). Significant differences in tumor location were observed between MB-RIG and ALL-RIG patients (p < 0.01). Gender distributions, age at RIG diagnosis (b) and latency period (c) between cranial irradiation and RIG diagnosis are shown with numbers in brackets indicating group size. MB-RIG patients displayed a wider distribution regarding the age at RIG diagnosis and latency period. RIG radiation-induced glioma, MB-RIG post-medulloblastoma RIG, ALL-RIG post-ALL RIG.