Table 2.
Top 20 (largest log2FC) differentially expressed genes (DEG) at 8 h simulated microgravity environment
| Name | log2FC | FDR | Description |
|---|---|---|---|
| snRNA | 5.05 | 1.96E-100 | Rn7SK small nuclear RNA |
| NR4A3 | 4.43 | 1.09E-70 | Nuclear receptor subfamily 4 |
| PPP1R15A | 3.83 | 3.84E-126 | Protein phosphatase regulatory (inhibitor) |
| FOSB | 3.40 | 2.87E-33 | FBJ osteosarcoma oncogene B |
| PIM1 | 3.39 | 2.55E-169 | Proviral integration site 1 |
| TBC1D9 | 3.02 | 1.17E-34 | TBC1 domain family |
| NR4A2 | 2.93 | 1.33E-61 | Nuclear receptor subfamily 4 |
| NUPR1 | 2.86 | 7.67E-40 | Nuclear protein transcription regulator 1 |
| GPER1 | 2.75 | 3.04E-19 | G protein-coupled estrogen receptor 1 |
| NECTIN4 | 2.68 | 1.48E-18 | Nectin cell adhesion molecule 4 |
| NEDD4 | 2.63 | 2.78E-35 | Neural precursor cell expressed |
| FGFR4 | 2.55 | 1.62E-16 | Fibroblast growth factor receptor 4 |
| GEM | 2.55 | 4.58E-17 | GTP binding protein |
| MAFF | 2.52 | 7.31E-26 | V-maf musculoaponeurotic fibrosarcoma oncogene family |
| FHDC1 | 2.42 | 3.61E-24 | FH2 domain containing 1 |
| CELSR2 | 2.38 | 2.49E-14 | Cadherin |
| RASGEF1B | 2.36 | 7.96E-24 | RasGEF domain family |
| FAM46C | 2.36 | 4.53E-14 | Family with sequence similarity 46 |
| HIST1H4N | 2.36 | 4.62E-14 | Histone cluster 1 |
| PLAT | 2.36 | 6.30E-18 | Plasminogen activator |